Transsphenoidal hypophysectomy (TSH)is performed with the patient administered a general endotracheal anesthetic,combined with a local anesthetic.The surgical team places the patient in a semisitting position,with the head against the headrest.A transnasal or a sublabial incision can be used for rapid access to the sella turcica.Select the diad (2)of conditions that would be appropriate indications for TSH.

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Endocrine pituitary disorders (such as Cushing's syndrome,acromegaly,malignant exophthalmos,and hypopituitarism resulting from intrasellar tumors),as well as nonpituitary disorders (such as advanced metastatic carcinoma of the breast and prostate,diabetic retinopathy,and uncontrollable severe diabetes),have been successfully treated by transsphenoidal hypophysectomy (TSH).Complete extracapsular enucleation of the pituitary in cases of hypophysectomy and possible complete removal of small pituitary tumors,with the remaining normal portion of the gland left intact,can be achieved.

Transsphenoidal Hypophysectomy (TSH)is Performed with the Patient Administered a General