Achieving hemostasis in delicate areas can be a challenge for the neurosurgeon.In addition to using meticulous technique to prevent bleeding,topical agents are routinely used as an adjunct to hemostasis.Some hemostatic products form a composite clot that seals a bleeding site by using a thrombin component that converts fibrinogen in the patient's blood to fibrin.Select the diad (2) of hemostatic products that provide hemostasis by topical application,essentially acting as a patch rather than a clotting factor.
A) Oxidized cellulose (Surgicel) and topical thrombin
B) Bone wax and topical thrombin
C) Bone wax and oxidized cellulose (Surgicel)
D) Gelatin matrix (FloSeal) and collagen hemostat (Avitene)
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