The tubuloglomerular feedback mechanism responds to an increase in
A) systemic blood pressure by signaling for a decrease in heart rate through blood-borne hormones.
B) urine production by signaling for a decrease in urine production through the hormone ADH.
C) NaCl concentration in tubular fluid by signaling for afferent arteriole constriction with local chemical messengers.
D) glomerular capillary hydrostatic pressure by signaling for afferent arterioles to constrict and increase filtration rate.

Question

Quizplus · Accepted Answer

The tubuloglomerular feedback mechanism involves the macula densa cells detecting increased NaCl concentration in the tubular fluid, which signals for the afferent arteriole to constrict, reducing glomerular filtration rate to maintain homeostasis.

The Tubuloglomerular Feedback Mechanism Responds to an Increase in