The Pure Food and Drugs Act and the Harrison Act were originally administered by the U.S.

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The Pure Food and Drugs Act and the Harrison Act were both originally administered by the Agriculture and Treasury Departments. The Pure Food and Drugs Act was passed in 1906 and aimed to prevent the misbranding and adulteration of food and drugs. It was largely enforced by the Bureau of Chemistry within the Department of Agriculture. The Harrison Act was passed in 1914 and aimed to regulate and tax the production, importation, and distribution of opium, cocaine, and their derivatives. It was enforced by the Bureau of Internal Revenue within the Treasury Department.