Baltimore's experiments to verify the existence of an RNA-dependent DNA polymerase required which of the following results in a viral replication assay? (Select all that apply)

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Baltimore's experiments demonstrated that RNA-dependent DNA polymerase (reverse transcriptase) is crucial for viral replication. Early addition of ribonuclease (A) would inhibit replication by degrading RNA, the template for reverse transcription. Preincubation with deoxyribonuclease (D) would inhibit replication by degrading DNA, the product of reverse transcription. Late incubation with deoxyribonuclease (E) would also inhibit replication by degrading newly synthesized viral DNA.

Baltimore's Experiments to Verify the Existence of an RNA-Dependent DNA