You are searching for a mutant strain of E.coli which is antibiotic resistant.What approach is most likely to be successful?

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Positive phenotypic selection involves exposing cells to a selection pressure, such as antibiotics, and then selecting for the cells that survive. This approach is likely to be successful in identifying antibiotic-resistant mutants within a population of E.coli. DNA sequencing would not necessarily identify antibiotic resistance, environmental searching may not yield a mutant strain, and toothpick pick-and-patching is not a commonly used approach for identifying mutants.

You Are Searching for a Mutant Strain of E