The "paired-end read" approach of Illumina sequencing suggests an approach in constructing DNA fragments to be read which is similar to that used in :

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Paired-end read approach of Illumina sequencing involves the fragmentation of the DNA into smaller pieces, which are then attached to adapters and amplified. These amplified fragments are then subjected to sequencing using the bridge amplification method. The paired-end sequence reads are generated by sequencing the DNA fragments from both ends, resulting in two reads for each fragment. This approach is similar to the pyrosequencing method, which also generates short reads from both ends of the DNA fragments, allowing the sequence to be assembled. The other options, Sanger dideoxy, Ion Torrent sequencing, and Maxam and Gilbert sequencing, all involve different methods of sequencing, and do not use the paired-end read approach.

The "Paired-End Read" Approach of Illumina Sequencing Suggests an Approach