Heat Shock Protein Protection Arises Because: (Select All That Apply)

Heat shock protein protection arises because: (Select all that apply)

A) their usually short half-life is reduced even further during high temperatures since all proteins in the cell are unfolding
B) they are particularly thermostable
C) the sigma factor which regulates their synthesis is more likely to be expressed at high temperature
D) competition with other unfolder peptides during growth at high temperatures extends their half life
E) all are correct explanations for the protection