Primary pathogens are distinguished from opportunistic pathogens in that they always cause a more severe disease.

Name: Primary pathogens are distinguished from opportunistic pathogens in that they always cause a more severe disease.
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Primary pathogens can cause disease in healthy hosts, while opportunistic pathogens cause disease primarily in individuals with a weakened immune system or when they gain access to an unusual location; the severity of the disease is not the distinguishing factor.

Primary Pathogens Are Distinguished from Opportunistic Pathogens in That They