The classical pathway of complement activation starts with the binding of C1 to the surface of the microbe by recognition of ANY of the following on the pathogen surface EXCEPT:

Question

Quizplus · Accepted Answer

Mannose-binding lectin initiates the lectin pathway of complement activation, not the classical pathway. The classical pathway is primarily activated by antibodies bound to the surface of a pathogen or by C-reactive protein.

The Classical Pathway of Complement Activation Starts with the Binding