β-lactam antibiotics bind to proteins located within the cell wall known as penicillin-binding proteins (PBPs).The enzymatic action of PBPs is to function as a(a)…

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Penicillin-binding proteins (PBPs) function as transpeptidases, which are enzymes involved in the cross-linking of peptidoglycan strands to form the bacterial cell wall. β-lactam antibiotics inhibit the transpeptidase activity of PBPs, leading to cell wall weakening and bacterial death.

β-Lactam Antibiotics Bind to Proteins Located Within the Cell Wall