This phase occurs 4 to 20 days after injury and involves rapid synthesis of collagen.

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The proliferative phase of healing occurs approximately 4 to 20 days after injury.The key cell in this phase of healing,the fibroblast,rapidly synthesizes collagen.Collagen synthesis provides the needed strength for a healing wound.The inflammatory phase begins immediately after injury.Vascular changes and cellular activity characterize this period.Changes in the severed vessels occur in an attempt to wall off the wound from the external environment.The maturation phase,or remodeling phase,of healing occurs from approximately 20 days after injury to longer than 1 year after injury.During this period,the wound develops tensile strength as collagen deposits form scar tissue.

This Phase Occurs 4 to 20 Days After Injury and Involves