A critically ill older adult is placed on a continuous infusion of high-dose loop diuretic for diuresis.The nurses knows to monitor for

Question

Quizplus · Accepted Answer

The senescent liver and kidneys are less able to metabolize and excrete drugs,leading to changes in absorption rates,time to peak plasma concentration,and clearance.Examples include high dosing regimens of diuretics to facilitate diuresis.Increased risk of metabolic acidosis then occurs because high diuretic doses increase competition for organic acid transport pathways at the proximal tubule.

A Critically Ill Older Adult Is Placed on a Continuous