Substances most likely to pass across the blood-brain barrier have what characteristics?
A) Low pH compared with body fluids
B) Lipid solubility
C) Large particle size
D) A close relation to toxic metabolites

Question

Quizplus · Accepted Answer

Passage of substances across the blood-brain barrier is a function of particle size,lipid solubility,and protein-binding potential.Most drugs or compounds that are lipid soluble and stable at body pH rapidly cross the blood-brain barrier.The blood-brain barrier is also very permeable to water,oxygen,carbon dioxide,and glucose.

Substances Most Likely to Pass Across the Blood-Brain Barrier Have