Which medication has a direct myocardial depressant effect on the heart?

Question

Quizplus · Accepted Answer

Ketamine has a direct myocardial depressant effect that is usually counterbalanced by its indirect effect on the autonomic nervous system to increase heart rate and blood pressure.Succinylcholine stimulates the cholinergic receptors,enhancing vagal tone,and it can produce sinus bradycardia or junctional escape rhythms.Opioids may cause bradycardia because of direct stimulation of the vagus nerve.Barbiturates depress the activity of the vasomotor center,causing peripheral vasodilation and hypotension.

Which Medication Has a Direct Myocardial Depressant Effect on the Heart