When Treated with Isoniazid,people Who Are Homozygous for an Allele

When treated with isoniazid,people who are homozygous for an allele associated with low N-acetyltransferase activity are at risk for which of the following?

A) Inability to maintain sufficient levels of isoniazid for treatment
B) Polyneuritis
C) Inability to absorb sufficient isoniazid
D) Hemolysis
E) Sudden death