Grünewald's Isenheim Altarpiece is characterized by ____.

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Grünewald's Isenheim Altarpiece is known for its highly emotional and realistic portrayal of pain and suffering, particularly in the depictions of Christ's crucifixion and the afflicted St. Sebastian. This style is a departure from the idealized forms and clear lines of High Renaissance art. The altarpiece was made for a hospital that specialized in treating patients with skin diseases, and Grünewald's representations of physical suffering were meant to provide comfort and empathy for the patients. Lutheran iconography is also present in the altarpiece, but it is not the defining character of the work. Finally, the altarpiece does not have a flat gold background, but instead features a complex and highly detailed landscape setting.

Grünewald's Isenheim Altarpiece Is Characterized by ____