Which route of drug administration causes the most significant hypersensitivity reaction?

Question

Quizplus · Accepted Answer

When the reaction occurs after parenteral administration (injection), it may be more severe because the allergen can be carried quickly to many parts of the body through the bloodstream. It takes more time for topically applied drugs to enter the bloodstream compared with parenterally applied (injected) drugs. It takes more time for a drug to enter the bloodstream via a patch compared with parenteral administration. It takes more time for oral medications to enter the bloodstream than parenterally applied drugs.

Which Route of Drug Administration Causes the Most Significant Hypersensitivity