The classic triad of symptoms seen in 25% of patients with Hand-Schüller-Christian disease includes all conditions except

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Cyclic neutropenia is an inherited disorder characterized by a cyclic decrease in the number of circulating neutrophils. Aphthous ulcers, gingival recession, and alveolar bone loss can be seen in association with this systemic condition. Well-defined or punched-out radiolucent areas in the skull are part of the triad of symptoms in chronic disseminated Hand-Schüller-Christian disease. Exophthalmos is a part of the triad of symptoms in chronic disseminated Hand-Schüller-Christian disease. Diabetes insipidus is part of the triad of symptoms in chronic disseminated Hand-Schüller-Christian disease.

The Classic Triad of Symptoms Seen in 25% of Patients