Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and

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Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and pheochromocytoma. The mucosal neuromas are prominent on the lips and the anterior dorsal surface of the tongue. They generally appear in the first few years of life. Medullary carcinoma of the thyroid has been diagnosed in more than 75% of patients with this syndrome; it generally develops in the second decade of life. Metastatic lesions develop frequently, and about 20% of patients die as a consequence of metastasis. Telangiectases are a component of Osler-Rendu-Parkes Weber syndrome. Gastrointestinal polyposis is associated with Peutz-Jeghers syndrome. Blue sclera is associated with osteogenesis imperfecta.

Multiple Mucosal Neuroma Syndrome Includes Multiple Mucosal Neuromas, Medullary Carcinoma