Mediterranean or Cooley anemia

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Mediterranean or Cooley anemia is called thalassemia major in the homozygous form, in which the genes on both chromosomes are involved. It is associated with severe hemolytic anemia, which results from damage to the red blood cell membranes and destruction of the red blood cells. Pernicious anemia is a vitamin B?? deficiency that is caused by a deficiency of intrinsic factor. Mediterranean or Cooley anemia has an autosomal inheritance pattern, and no predilection for either sex is seen. Dietary deficiencies of folic acid and vitamin B?? can result in anemia and can occur in association with malnutrition and increased metabolic requirements; however, Mediterranean or Cooley anemia is not caused by a dietary or folic acid deficiency.

Mediterranean or Cooley Anemia