Increased levels of vitamins B₆ and B₁₂ have been noted in women taking oral contraceptive agents (OCAs) due to increased levels of estrogen. Progestins within OCAs can cause weight gain related to increased appetite and related carbohydrate metabolism.

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Low levels of vitamins B₆ and B₁₂ have been noted in women using OCAs. Note that low levels of B₆ are associated with risk for chronic inflammation. Although progestins can cause weight gain related to increased appetite and altered carbohydrate metabolism, estrogens can lead to an increase in subcutaneous fat and fluid retention.

Increased Levels of Vitamins B6 and B12 Have Been Noted

Increased Levels of Vitamins B₆ and B₁₂ Have Been Noted