Approximately 33% of older adults take multiple prescription drugs and multiple dietary supplements. Mature renal and liver function in older adults facilitates clearance of medications from the body.

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Note that approximately 33% of older adults take three or more prescription drugs and three or more supplements. Also pertinent, 10% combine five or more prescription drugs with as many dietary supplements. The potential for drug interactions and interference with appetite and nutrient absorption is great. Liver and renal clearance of these substances is decreased because of physiologic and pathophysiologic changes. These effects result in greater variability of drug action and less predictability of a drug's effects.

Approximately 33% of Older Adults Take Multiple Prescription Drugs and Multiple