Which one of the following is the primary difference between an anaphylactic reaction and an anaphylactoid reaction?

Question

Quizplus · Accepted Answer

The primary difference between an anaphylactic reaction and an anaphylactoid reaction is that an anaphylactoid reaction may occur without prior sensitization to the antigen, while anaphylaxis requires prior sensitization. In both types of reactions, the body releases histamines and other chemicals that cause symptoms such as hives, swelling, and difficulty breathing. However, anaphylactoid reactions are not mediated by IgE antibodies like anaphylaxis, and are instead caused by direct activation of mast cells and basophils. Epinephrine is indicated for both types of reactions, but may be less effective in anaphylactoid reactions due to the different mechanism of action.

Which One of the Following Is the Primary Difference Between