What causes numbness and tingling in the fingers of individuals with untreated pernicious anemia?

Question

Quizplus · Accepted Answer

Pernicious anemia is caused by a deficiency of vitamin B₁₂, which is important for proper nervous system functioning. Untreated pernicious anemia can result in peripheral nerve damage and demyelination, leading to numbness and tingling in the fingers. Persistent hyperbilirubinemia (A) is a symptom of liver disease, not pernicious anemia. Increasing acidosis affecting metabolism (B) is not a common complication of pernicious anemia. Multiple small vascular occlusions affecting peripheral nerves (D) may be seen in conditions such as diabetes, but are not a typical feature of pernicious anemia.

What Causes Numbness and Tingling in the Fingers of Individuals