Prolonged or severe stress predisposes to peptic ulcer disease because:

Question

Quizplus · Accepted Answer

Prolonged or severe stress can lead to the release of cortisol and catecholamines which can reduce blood flow to the gastric wall and mucous glands, making the gastric mucosa more susceptible to acid and pepsin damage, leading to peptic ulcer disease. Reduced bicarbonate content in bile and pancreatic secretions, increased acid/pepsinogen secretion, and increased motility are not directly related to the development of peptic ulcer disease due to stress.

Prolonged or Severe Stress Predisposes to Peptic Ulcer Disease Because