Which enzyme recognizes a specific nucleotide sequence (~4-8 nucleotides in length)and catalyzes the digestion of the nucleic acid at that site, causing a break in the DNA strand?

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Endonucleases recognize a specific nucleotide sequence (usually four to eight nucleotides in length)known as the enzyme's recognition or restriction site.

Which Enzyme Recognizes a Specific Nucleotide Sequence (~4-8 Nucleotides in Length)and