Huntington's disease, a fatal degenerative movement disorder, results from large numbers of codon repeats in the Huntingtin gene located on chromosome 4. This means that the
A) extra codon repeats will not impact the individual's phenotype.
B) affected Huntington gene will be silenced, producing no protein.
C) affected Huntington gene will produce a protein with abnormally large amounts of the amino acid encoded by the extra codons.
D) affected Huntington gene will produce a protein with abnormally small amounts of the amino acid encoded by the extra codons.

Question

Quizplus · Accepted Answer

The extra codon repeats in the Huntington gene will result in the production of a protein with abnormally large amounts of the amino acid encoded by the extra codons. This abnormal protein accumulation leads to the degenerative movement disorder characteristic of Huntington's disease. A is incorrect because extra codon repeats do have an impact on the individual's phenotype. B is incorrect because the affected gene still produces a protein, albeit an abnormal one. D is incorrect because the extra codons result in more of the encoded amino acid, not less.

Huntington's Disease, a Fatal Degenerative Movement Disorder, Results from Large