Queen Victoria of England had a son, Leopold, and a great-grandson, Tsarevich Alexei Nikolaevich Romanov of Russia, both of whom had hemophilia. We can conclude that

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Queen Victoria was not affected by hemophilia, but she was a carrier for the disease. This means that she carried the gene for hemophilia on one of her two X chromosomes, which she passed on to her son Leopold, and potentially to other descendants. Hemophilia is a sex-linked recessive genetic disorder, meaning that it primarily affects males who inherit the defective X chromosome from their mother. It is unlikely that Prince Albert was a carrier, as the hemophilia gene was not present in his family tree. The likelihood of spontaneous mutation is also low, as hemophilia is a rare disorder with a low mutation rate.

Queen Victoria of England Had a Son, Leopold, and a Great-Grandson