Scleroderma Is an Autoimmune Disease in Which Repeated Bouts of Inflammation

Scleroderma is an autoimmune disease in which repeated bouts of inflammation result in collagen deposits in the skin.Which would be a symptom of scleroderma?

A) increased blood flow to the skin
B) increased flexibility in the skin
C) change in the skin cell type from squamous to columnar
D) change in the skin cell type from columnar to squamous
E) less flexibility and sensitivity to temperature in the skin