If a father is affected by an X-linked recessive condition and the mother is a carrier,what is the probability of their children being affected?

Question

Quizplus · Accepted Answer

In the case of an X-linked recessive condition, if the father is affected (having only one X chromosome, which carries the condition) and the mother is a carrier (having one affected X chromosome and one unaffected X chromosome), their sons have a 50% chance of being affected. This is because sons inherit their X chromosome from their mother and their Y chromosome from their father. Daughters inherit one X chromosome from each parent, but since they receive the father's affected X chromosome, they will be carriers if they inherit the mother's unaffected X chromosome.

If a Father Is Affected by an X-Linked Recessive Condition