The mass extinction at the end of the Permian period (about 250 million years ago)is thought to have killed off as many as 60 percent of the animal families.What group of animals dominated life on land at that time?

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Reptiles, specifically synapsids (which include early mammal ancestors), dominated life on land during the end of the Permian period. Trilobites were extinct by this time, and mammals had not yet evolved. Amphibians were present but not as dominant as the reptiles.

The Mass Extinction at the End of the Permian Period