Once a ligand binds to a receptor-enzyme,
A)the catalytic domain interacts with extracellular components.
B)the catalytic domain interacts with intracellular components.
C)the ligand-binding domain is phosphorylated.
D)the ligand-binding domain is dephosphorylated.

Question

Quizplus · Accepted Answer

Enzyme-receptors are transmembrane proteins that contain both a ligand-binding domain and a catalytic domain. When a ligand binds to the receptor-enzyme, it induces a conformational change that activates the catalytic domain, causing it to interact with intracellular components such as second messenger molecules or other enzymes. Therefore, choice B is the correct answer. Choices A, C, and D are incorrect because they do not describe the correct sequence of events that occur when a ligand binds to a receptor-enzyme.

Once a Ligand Binds to a Receptor-Enzyme