Which of the following side effects are consistent with chronic administration of theophylline?
I.Nausea
II.Vomiting
III.Tachycardia
IV.Central nervous system stimulation

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The use of theophylline to treat chronic childhood asthma is problematic due to potentially serious short-term and long-term adverse events.Dose-related acute toxicities include tachycardia,nausea,vomiting,supraventricular tachycardia,central nervous system stimulation,seizures,headache,and electrolyte disturbances.Adverse events seen at therapeutic serum concentrations include insomnia,gastric upset,and hyperactivity.

Which of the Following Side Effects Are Consistent with Chronic