A lesion in the indirect pathway of the basal ganglia would most likely result in:

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The function of the indirect pathway is to excite the globus palladus internal.The excitation results in inhibition to the thalamus,since the role of the globus palladus internal is to inhibit the thalamus.If there is a lesion to the pathway,the basal ganglia are out of balance,resulting in a lack of inhibition to the thalamus and therefore increased excitation of the cortex.

A Lesion in the Indirect Pathway of the Basal Ganglia