How is the sensation of itch similar to the sensation of pain?

Question

Quizplus · Accepted Answer

Both pain and itch are interpreted as unpleasant sensations by the brain. This is because both involve the activation of the nerve fibers that transmit signals related to tissue damage, inflammation, or irritation. The difference between pain and itch lies in the specific type of nerve fibers that are involved, as well as the different brain regions that process the signals. While pain is typically associated with the activation of small, myelinated A-delta fibers and unmyelinated C-fibers, itch is mainly caused by the activation of C-fibers alone. However, both pain and itch can elicit a similar emotional response, such as agitation, frustration, or discomfort, and can even lead to a withdrawal response, such as scratching or rubbing the affected area, to try to alleviate the sensation.

How Is the Sensation of Itch Similar to the Sensation