The dorsal column-medial lemniscal pathway is a pathway for the nociceptors (pain) and thermoreceptors (temperature) that travels up the contralateral side of spinal column and does not synapse in the brain until the ventral posterior nucleus of the thalamus.

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The dorsal column-medial lemniscal pathway is a pathway for the mechanoreceptors (touch and pressure) and proprioceptors (sensory information from muscles and joints) that travel up the contralateral side of the spinal column and synapse in the dorsal column nuclei before crossing over to the contralateral side and ascending to the ventral posterior nucleus of the thalamus.

The Dorsal Column-Medial Lemniscal Pathway Is a Pathway for the Nociceptors