Which is the most likely explanation for the defect in dystrophic epidermolysis bullosa, in which the skin blisters in response to any touch?
A)The skin has too many melanocytes that produce too much melanin.
B)Melanocytes cannot produce melanin.
C)Collagen fibrils that attach the epidermis to the dermis break down.
D)The skin layers are reversed.

Question

Quizplus · Accepted Answer

Dystrophic epidermolysis bullosa is caused by a defect in the collagen fibrils that anchor the epidermis to the dermis. As a result, any mechanical stress or touch can cause the skin to blister and peel away from the underlying tissue. This defect can be caused by mutations in the genes that code for collagen or other proteins involved in the formation and maintenance of the extracellular matrix. The other choices (A, B, and D) are not related to the pathology of dystrophic epidermolysis bullosa.

Which Is the Most Likely Explanation for the Defect in Dystrophic