The order in which HIV breaches barriers and affects immunity is
A)inhalation, entering the circulation, entering helper T cells.
B)ingestion, entering the circulation, entering helper T cells.
C)crossing the mucosal barrier, entering macrophages, then B cells, then natural killer cells.
D)crossing the mucosal barrier, entering macrophages, entering helper T cells, then cytotoxic T cells.

Question

Quizplus · Accepted Answer

HIV initially breaches the mucosal barrier which includes the mucous membranes of the genital, anal, and oral areas. The virus then enters macrophages and dendritic cells within those regions. From there, HIV can enter into B cells, but it mainly enters into CD4+ helper T cells, which are important for immune system regulation. Finally, HIV can infect cytotoxic T cells which are responsible for targeting infected cells. Therefore, the correct order is crossing the mucosal barrier, entering macrophages, entering helper T cells, and then cytotoxic T cells.

The Order in Which HIV Breaches Barriers and Affects Immunity