The Cells in Many Late-Stage Precancerous Polyps in the Human

The cells in many late-stage precancerous polyps in the human colon usually contain

A) normal tumor suppressor genes and at least one oncogene.
B) one inactive and one active copy of a tumor suppressor gene and normal proto-oncogenes.
C) two inactive copies of a tumor suppressor gene and two proto-oncogenes.
D) two inactive copies of a tumor suppressor gene and one oncogene.