The myocardium is the thickest in the right atrium chamber because it must work the hardest to pump blood to the entire body.

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The myocardium, or heart muscle tissue, is actually thickest in the left ventricle chamber. This is because the left ventricle is responsible for pumping oxygen-rich blood to the entire body, so it needs more muscle to generate the necessary force to push blood through the systemic circulation. The right atrium pumps blood to the lungs for oxygenation, which requires less force and therefore less myocardial thickness.

The Myocardium Is the Thickest in the Right Atrium Chamber