In the absence of ATP,myosin can remain bound to actin;this can occur during times when there is a significant reduction in intracellular ATP.

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In the absence of ATP, the myosin head cannot detach from actin and remains in a conformation that is unable to bind ATP. This can occur during times of reduced ATP availability, such as during intense exercise or cardiac ischemia.

In the Absence of ATP,myosin Can Remain Bound to Actin;this