Some women (including Angelina Jolie)with mutations in tumor suppressor genes,opt for oophorectomy (removal of their ovaries)to decrease their risk of some types of cancer.Unless they take supplements,they probably will have lower circulating levels of both androgens and estrogen.

Question

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Ovaries are major sites of estrogen and androgen production in women. Removal of the ovaries will lead to lower circulating levels of both hormones unless supplemented.

Some Women (Including Angelina Jolie)with Mutations in Tumor Suppressor Genes,opt