Normally,all the H⁺ ions generated from CO₂ in tissue capillaries recombine with bicarbonate in pulmonary capillaries and are removed from the body as CO₂.

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This is known as the bicarbonate buffer system, which helps regulate pH in the body. The H⁺ ions from CO₂ generated in tissue capillaries combine with bicarbonate ions to form carbonic acid, which eventually breaks down into CO₂ and H₂O in the pulmonary capillaries and is exhaled out of the body. This process helps maintain a balance of acids and bases in the body.

Normally,all the H⁺ Ions Generated from CO₂ in Tissue Capillaries