The kidneys work to rectify metabolic acidosis and alkalosis but have no effect on respiratory acidosis and alkalosis.

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The kidneys can also help to compensate for respiratory acidosis and alkalosis by adjusting the reabsorption and excretion of bicarbonate ions in response to changes in the partial pressure of carbon dioxide (PCO2) in the blood. However, this compensation is slower and less effective than the immediate buffering response of the respiratory system.

The Kidneys Work to Rectify Metabolic Acidosis and Alkalosis but Have