Chiara has poorly controlled pain from diabetic neuropathy.What serotonin norepinephrine reuptake inhibitor might be given as an adjuvant?

Question

Quizplus · Accepted Answer

Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that has been found to be effective in treating diabetic neuropathy pain. It works by increasing the levels of both serotonin and norepinephrine in the brain, which helps to reduce pain perception. Nortriptyline, an older tricyclic antidepressant, may also be effective as an adjuvant for neuropathic pain but has more potential for side effects compared to duloxetine. Carbamazepine is an anticonvulsant used for neuropathic pain while pregabalin is an alpha-2-delta subunit ligand of voltage-gated calcium channels and is also used for neuropathic pain. However, neither of these are SNRIs.

Chiara Has Poorly Controlled Pain from Diabetic Neuropathy