Osteoblasts themselves are able to monitor extracellular calcium levels.

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Osteoblasts are bone-forming cells that are responsible for the formation of new bone tissue. They play a crucial role in the regulation of extracellular calcium levels, as they are able to detect changes in the concentration of calcium ions in the surrounding environment. Once calcium levels are detected to be low, osteoblasts secrete a hormone called osteocalcin, which stimulates the release of calcium from the bones, thereby increasing its concentration in the bloodstream.

Osteoblasts Themselves Are Able to Monitor Extracellular Calcium Levels