Which statement explains how the lack of dopamine physiologically affects those individuals suffering from Parkinson disease?
A) Without dopamine, the excitatory effects of acetylcholine are not restrained, thus postural muscles are overstimulated.
B) Without dopamine, the excitatory effects of acetylcholine are inhibited, thus relaxing postural muscles.
C) Without dopamine, the inhibitory effects of acetylcholine are not restrained, thus postural muscles are overstimulated.
D) Without dopamine, the inhibitory effects of acetylcholine are restrained, thus relaxing postural muscles.

Question

Quizplus · Accepted Answer

In Parkinson's disease, the lack of dopamine leads to an imbalance in the neurotransmitter system of the brain. Dopamine normally acts to inhibit the excitatory effects of acetylcholine. Without sufficient dopamine, acetylcholine's excitatory effects are unchecked, leading to overstimulation of postural muscles, which contributes to the symptoms of Parkinson's disease.

Which Statement Explains How the Lack of Dopamine Physiologically Affects