Filtrate in the descending limb of the nephron loop has the highest osmolality.

Question

Quizplus · Accepted Answer

Filtrate in the descending limb of the nephron loop is in close proximity to the highly concentrated renal medulla, which creates a gradient for water to passively diffuse out of the nephron and into the surrounding interstitial fluid. This leads to an increase in osmolality within the filtrate as it moves down the descending limb, reaching its highest point at the bend of the nephron loop.

Filtrate in the Descending Limb of the Nephron Loop Has