Why are proton pump inhibitors often included as part of the pharmacologic treatment regimen for clients with rheumatoid arthritis (RA)?
A)Proton pump inhibitors help reduce the unpleasant GI-related side effects of NSAIDs, which are the most common class of medications used in the treatment of RA.
B)Proton pump inhibitors can dramatically decrease both inflammation and immune reactions and appear to slow the progression of joint destruction in RA.
C)Proton pump inhibitors help reduce the body's autoimmune response, thereby limiting the effects of the autoimmune disease process that underlies RA.
D)Proton pump inhibitors help reduce the risk of retinitis and vision loss in clients who are taking antimalarial agents as part of their therapeutic regimen for RA.

Question

Quizplus · Accepted Answer

A)NSAIDs are among the most common dugs used in the treatment of RA, although they may produce unpleasant gastric side effects like stomach lining irritation, erosions, and bleeding ulcers. Concurrent administration of proton pump inhibitors may reduce the risk for GI bleeding due to NSAIDs. Proton pump inhibitors do not affect the inflammation, immune reactions, and joint destruction associated with RA, nor do they reduce the body's autoimmune response. Furthermore, these drugs do not affect the risk of vision problems that accompanies use of antimalarial agents.
B)NSAIDs are among the most common dugs used in the treatment of RA, although they may produce unpleasant gastric side effects like stomach lining irritation, erosions, and bleeding ulcers. Concurrent administration of proton pump inhibitors may reduce the risk for GI bleeding due to NSAIDs. Proton pump inhibitors do not affect the inflammation, immune reactions, and joint destruction associated with RA, nor do they reduce the body's autoimmune response. Furthermore, these drugs do not affect the risk of vision problems that accompanies use of antimalarial agents.
C)NSAIDs are among the most common dugs used in the treatment of RA, although they may produce unpleasant gastric side effects like stomach lining irritation, erosions, and bleeding ulcers. Concurrent administration of proton pump inhibitors may reduce the risk for GI bleeding due to NSAIDs. Proton pump inhibitors do not affect the inflammation, immune reactions, and joint destruction associated with RA, nor do they reduce the body's autoimmune response. Furthermore, these drugs do not affect the risk of vision problems that accompanies use of antimalarial agents.
D)NSAIDs are among the most common dugs used in the treatment of RA, although they may produce unpleasant gastric side effects like stomach lining irritation, erosions, and bleeding ulcers. Concurrent administration of proton pump inhibitors may reduce the risk for GI bleeding due to NSAIDs. Proton pump inhibitors do not affect the inflammation, immune reactions, and joint destruction associated with RA, nor do they reduce the body's autoimmune response. Furthermore, these drugs do not affect the risk of vision problems that accompanies use of antimalarial agents.

Why Are Proton Pump Inhibitors Often Included as Part of the Pharmacologic